E-learning in analysis of genomic and proteomic data 2. Data analysis 2.2. Analysis of high-density genomic data 2.2.1. DNA microarrays Analysis of arrayCGH

Other types of methods do not perform segmentation but directly cluster the clones based on their genome order position. Such a clustering approach is due to Wang et al. [53]. Their method known as CLAC (CLuster Along Chromosomes) consists of a modification of hierarchical clustering, with special distance metrics taking advantage of the information about rank-order-dependence of genes. A strong point of this method is that it additionally provides an estimate of the false discovery rate.