přihlášení*
Login Name:
Heslo*:

Logo IdP Autentization for MU's Faculty of Medical people
bez nutnosti registrace* [ ? ]


Search

Podrobně prohledat*
Search
Languages

Rubriky*
titulky rubrik*
anotace rubrik* 		Studie*
titulky studií*
anotace studií* 		Obrázky*
titulky obrázků*
popisy obrázků*
klíčová slova*

Výsledky hledání*

Nalezené studie* (n=2)

id název* obrázků* autor* vytvořeno* modifikováno* schváleno* schválil*
158 cs: Megaloblastová anémie
en: Megaloblastic anemia 		19 Monika Antošová, A. Buliková, J. Kissová 27.5.2008, 21:43 20.6.2008, 13:40 20.6.2008, 13:40 J. Kissová
66 cs: Cabotovy prstence
en: Cabot´s rings 		1 S. Valníček 23.3.2007, 12:14 3.12.2007, 18:29 3.12.2007, 18:29 Jan Blatný


Nalezené obrázky* (n=29)

AML with multilineage dysplasia - BM
The myeloblasts are the most frequent cells of the picture, some of them are in mitosis. In erythroid lineage are megaloblastoid features - markedly expressed in two cells at 4-5 o'clock. Hypogranulation is in neutrophils. / Myeloblasty jsou nejčastějšími buňkami obrázku, některé z nich jsou v mitóze. V erytroidní řadě jsou megaloblastoidní rysy - zřetelně vyjádřeny ve dvou buňkách na 4-5. hodině. Hypogranulace je v neutrofilech. Description: The myeloblasts are the most frequent cells of the picture, some of them are in mitosis. In erythroid lineage are megaloblastoid features - markedly expressed in two cells at 4-5 o'clock. Hypogranulation is in neutrophils.
Type: bone marrow
Klíčová slova*: myeloblast, hypogranulation, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Numerous myeloblast and cells of erythroid lineage (almost 50%) are dominant populations of the cells of the bone marrow smear. The cells of erythroid series show dysplastic features - multilobularity, non-round nucleus shape (at 11o'clock), megaloblastoid features (at 9 o'clock) and failure of cytoplasm hemoglobinization (at 3 o'clock). / Početné myeloblasty a buňky erytroidní linie (téměř 50%) jsou dominujícími populacemi buněk v nátěru kostní dřeně. Buňky erytroidní řady vykazují dysplastické rysy - multilobularitu, zneokrouhlený tvar jádra (na 11. hodině), megaloblastoidní rysy (na 9. hodině) a poruchu hemoglobinizace cytoplazmy (na 3. hodině). Description: Numerous myeloblast and cells of erythroid lineage (almost 50%) are dominant populations of the cells of the bone marrow smear. The cells of erythroid series show dysplastic features - multilobularity, non-round nucleus shape (at 11o'clock), megaloblastoid features (at 9 o'clock) and failure of cytoplasm hemoglobinization (at 3 o'clock).
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Three myeloblast and six erythroid cells (and one naked nucleus) are in the picture. Two immature erythroid cells with abundant basophilic cytoplasm are megalobasts. At the lower left is one more cell probably of granulocytic lineage; it has a few cytoplasmic a one nuclear inclusions of not clear origin - some of them can be digestive ones after haemophagocytosis (one at 6 o'clock in the cell). / Na obrázku jsou tři myeloblasty a šest buněk erytropoezy (a jedno holé jádro). Dvě nezralé erytroidní buňky s bohatou bazofilní cytoplazmou jsou megaloblasty. Nalevo dole je jedna buňka pravděpodobně granulocytární řady; má pár cytoplazmatických a jednu jadernou inkluzi nejasného původu - některé z nich mohou být ztrávené po hemofagocytóze (jedna na 5. hodině v buňce). Description: Three myeloblast and six erythroid cells (and one naked nucleus) are in the picture. Two immature erythroid cells with abundant basophilic cytoplasm are megalobasts. At the lower left is one more cell probably of granulocytic lineage; it has a few cytoplasmic a one nuclear inclusions of not clear origin - some of them can be digestive ones after haemophagocytosis (one at 6 o'clock in the cell).
Type: bone marrow
Klíčová slova*: myeloblast, megaloblast, haemophagocytosis
AML with multilineage dysplasia - BM
Immature cells, some of them are destroyed. Bi-lobar and megaloblastoid late erythroblast is at the right from the centre. Two micro-forms of megakaryocytes are underneath the picture's centre. / Nezralé buňky, některé z nich jsou poškozené. Bilobární a megaloblastoidní pozdní erytroblast je napravo od centra. Dvě mikroformy megakaryocytů jsou pod centrem obrázku. Description: Immature cells, some of them are destroyed. Bi-lobar and megaloblastoid late erythroblast is at the right from the centre. Two micro-forms of megakaryocytes are underneath the picture's centre.
Type: bone marrow
Klíčová slova*: megakaryocyte, megaloblast
AML with multilineage dysplasia - BM
There are seven myeloblasts underneath the centre of the picture and three proerythroblasts at the upper left. Between these two groups of the cells lies one agranular band and one red mitosis. Two early polychromatophil red cells precursors (upper left) have megaloblastoid nuclear pattern and they are bilobated. Three late polychromatophil normoblasts (to the left and down from the centre) have pycnotic nuclei. / Pod centrem obrázku je sedm myeloblastů a tři proerytroblasty jsou vlevo nahoře. Mezi těmito dvěma skupinami buněk leží jedna agranulární tyčka a jedna červená mitóza. Dva časné polychromatofilní prekurzory erytrocytů mají megaloblastoidní vzhled jádra a jsou bilobární. Tři pozdní polychromatofilní normoblasty (doleva a dolu z centra) mají pyknotická jádra. Description: There are seven myeloblasts underneath the centre of the picture and three proerythroblasts at the upper left. Between these two groups of the cells lies one agranular band and one red mitosis. Two early polychromatophil red cells precursors (upper left) have megaloblastoid nuclear pattern and they are bilobated. Three late polychromatophil normoblasts (to the left and down from the centre) have pycnotic nuclei.
Type: bone marrow
Klíčová slova*: myeloblast, proerythroblast, polychromatophilic normoblast, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Myeloblasts represent about 30% of all nucleated bone marrow cells. There is also erythroid hyperplasia here - almost 50% in bone marrow cells differential count. Cells of erythroid lineage show dysplastic features - megaloblastic nuclei, bilnuclear cells or nuclear lobulisation, internuclear bridges, poorly hemoglobinised cytoplasm. These dysplastic features are presented in more than 50% of erythroid cells. / Myeloblasty představují asi 30% ze všech jaderných buněk dřeně. Je zde taktéž erytroidní hyperplázie - téměř 50% v diferenciálním rozpočtu buněk kostní dřeně. Buňky erytroidní řady ukazují dysplastické rysy - megaloblastoidní jádra, binukleární buňky nebo jadernou lobulizaci, mezijaderné můstky, špatně hemoglobinizovanou cytoplazmu. Tyto dysplastické rysy jsou přítomny ve více než 50% erytroidních buněk. Description: Myeloblasts represent about 30% of all nucleated bone marrow cells. There is also erythroid hyperplasia here - almost 50% in bone marrow cells differential count. Cells of erythroid lineage show dysplastic features - megaloblastic nuclei, bilnuclear cells or nuclear lobulisation, internuclear bridges, poorly hemoglobinised cytoplasm. These dysplastic features are presented in more than 50% of erythroid cells.
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis, internuclear bridges
Megaloblastic haematopoiesis- PB
There are macrocytes and also characteristic oval macrocytes in peripheral blood smear. There is also some degree of anisocytosis and poikilocytosis in this rather severe case, including the presence of tear-drop poikilocytes, fragments. / V nátěru periferní krve jsou makrocyty a charakteristické makroovalocyty. U tohoto spíše závažnějšího případu je přítomen i jistý stupěň anicytózy, poikilocytózy, včetně přítomnosti slzičkovitých poikilocytů, fragmentů. Description: There are macrocytes and also characteristic oval macrocytes in peripheral blood smear. There is also some degree of anisocytosis and poikilocytosis in this rather severe case, including the presence of tear-drop poikilocytes, fragments.
Type: peripheral blood
Klíčová slova*: poikilocyte, makrocyte, anisocytosis
Megaloblastic haematopoiesis- PB
Cabot ring can be find in severe case of megaloblastic erythropoiesis. / U těžkého případu megaloblastické erytropoézy může být nalezen Cabotův prstenec. Description: Cabot ring can be find in severe case of megaloblastic erythropoiesis.
Type: peripheral blood
Klíčová slova*: Cabot ring
Megaloblastic haematopoiesis- PB
The presence of hypersegmented neutrophils is highly suggestive of megaloblastic haematopoiesis in peripheral blood smear although not patognomic. It persists for a week or more after commencement of of vitamin B12 or folic acid therapy. / Přítomnost hypersegmentovaných neutrofilů v nátěru periferní krve je vysoce suspektní z megaloblastické hematopoézy, i když ne patognomická. Přetrvává týden i více po zavedení léčby vitamínem B12 či kyselinou listovou. Description: The presence of hypersegmented neutrophils is highly suggestive of megaloblastic haematopoiesis in peripheral blood smear although not patognomic. It persists for a week or more after commencement of of vitamin B12 or folic acid therapy.
Type: peripheral blood
Klíčová slova*: hypersegmentation
Megaloblastic erythropoiesis- KD
Macrophage contains erythroid precursors. It is also fully filed with iron. / Makrofág obsahuje erytroidní prekurzory. Je takéž zcela vyplněn železem. Description: Macrophage contains erythroid precursors. It is also fully filed with iron.
Type: bone marrow
Klíčová slova*: macrophage, iron stain
Megaloblastic erythropoiesis- BM
Storage iron is usually increased in case of megaloblastic erythropoiesis. Haemophagocytosis is also shown here. / U megaloblastové přestavy je obvykle zvýšeno zásobní železo. Zde je rovněž přítomna hemofagocytóza. Description: Storage iron is usually increased in case of megaloblastic erythropoiesis. Haemophagocytosis is also shown here.
Type: bone marrow
Klíčová slova*: iron stain, haemophagocytosis
Megaloblastic haematopoiesis- BM
Siderotic granules in Pearl's stain in sideroblast are abnormally prominent, sometimes occasional ring sideroblast can also occur (not shown). / Siderotická granula v Perlsově barvení jsou v sideroblastu abnormálně prominující, občas se může objevit i prstenčitý sideroblast (neukázáno). Description: Siderotic granules in Pearl's stain in sideroblast are abnormally prominent, sometimes occasional ring sideroblast can also occur (not shown).
Type: bone marrow
Klíčová slova*: sideroblast, iron stain, Perls´stain
Megaloblastic haemotopoiesis- BM
An iron stain shows numerous sideroblast (in the middle) and siderocytes. / Barvení na železo prokazuje četné sideroblasty (uprostřed) a siderocyty. Description: An iron stain shows numerous sideroblast (in the middle) and siderocytes.
Type: bone marrow
Klíčová slova*: siderocyte, sideroblast, iron stain
Megaloblastic erytropoiesis- BM
The mitotic rate is increased. This picture shows intercellular bridge between two megaloblasts. / Je zvýšena mitotická aktivita. Tento obrázek ukazuje mezibuněčný můstek mezi dvěma megaloblasty. Description: The mitotic rate is increased. This picture shows intercellular bridge between two megaloblasts.
Type: bone marrow
Klíčová slova*: megaloblast
Megaloblasic erythropoiesis- BM
Multilobular erythroblast can also occur, but this feature is less strongly associated with megaloblastic erythropoiesis unless co-existing myelodysplastic syndrome. / Může se taktéž objevit vícejaderný erytroblast, ale tento nález je méně významně spojen s megaloblastovou přestavbou pokud není současně přítomen myelodysplastický syndrom. Description: Multilobular erythroblast can also occur, but this feature is less strongly associated with megaloblastic erythropoiesis unless co-existing myelodysplastic syndrome.
Type: bone marrow
Klíčová slova*: dysplasia
Megaloblastic erythropoiesis- BM
More (at right) or less (at left) mature megaloblasts with abundant cytoplasm. The more mature one contains numerous Howell Jolly bodies. Erythrocyte at the middle left shows basophilic stippling - this picture can be find also in peripheral blood smears. / Více (vpravo) či méně (vlevo) zralé megaloblasty s objemnou cytoplazmou. Ten více zralý obsahuje četná Howell- Jollyho tělíska. Erytrocyt vlevo uprostřed ukazuje basofilní tečkování - tento obraz může být nalezen i v nátěrech periferní krve. Description: More (at right) or less (at left) mature megaloblasts with abundant cytoplasm. The more mature one contains numerous Howell Jolly bodies. Erythrocyte at the middle left shows basophilic stippling - this picture can be find also in peripheral blood smears.
Type: bone marrow
Klíčová slova*: basophilic stippling, Howell-Jolly body
Megaloblastic haematopoiesis- BM
Mitoses are more frequent in bone marrow (mitosis of granulocytic lineage at left, erythroid mitosis at right). Cell in metaphase shows that chromosomes are unusually long. / V kostní dřeni jsou častější mitózy (mitóza granulocytární řady vlevo, erytroidní mitóza vpravo). Buňka v metafázi ukazuje neobvykle dlouhé chromozomy. Description: Mitoses are more frequent in bone marrow (mitosis of granulocytic lineage at left, erythroid mitosis at right). Cell in metaphase shows that chromosomes are unusually long.
Type: bone marrow
Klíčová slova*: mitosis
Megaloblastic haematopoiesis- BM
Megaloblastic erythropoiesis is ineffective, early erythroid cells are over-represented in comparison with mature cells. Macrophages are increased and contain defective red cell precursors and cellular debris. / Megaloblastická erytropoéza je inefektivní, časné erytroidní buňky jsou častěji zastoupeny v porovnání s buňkami zralými. Je zvýšen počet makrofágů a obsahují defektní erytroidní prekurzory a zbytky buněk. Description: Megaloblastic erythropoiesis is ineffective, early erythroid cells are over-represented in comparison with mature cells. Macrophages are increased and contain defective red cell precursors and cellular debris.
Type: bone marrow
Klíčová slova*: macrophage, haemophagocytosis
Megaloblastic haematopoiesis- BM
Hypersegmented moderately mature megakaryocyte. / Hypersegmentovaný středně zralý megakaryocyt. Description: Hypersegmented moderately mature megakaryocyte.
Type: bone marrow
Klíčová slova*: megakaryocyte
Megaloblastic haematopoiesis- BM
Mature megakaryocyt with more finely stippled chromatin then normal megakaryocytes. / Zralý megakaryocyt s jemněji tečkovaným chromatinem než u normálních megakaryocytů. Description: Mature megakaryocyt with more finely stippled chromatin then normal megakaryocytes.
Type: bone marrow
Klíčová slova*: megakaryocyte
Megaloblastic erythropoiesis- BM
Some early and late (at right) megaloblasts, one promegaloblast at middle left. Both types of megaloblasts have abundant cytoplasm and rather immature nuclear chromatin. / Několik časných a pozdních (vpravo) megaloblastů, jeden promegaloblast vlevo uprostřed. Oba typy megaloblastů mají objemnou cytoplazmu a spíše nezralý jaderný chromatin. Description: Some early and late (at right) megaloblasts, one promegaloblast at middle left. Both types of megaloblasts have abundant cytoplasm and rather immature nuclear chromatin.
Type: bone marrow
Klíčová slova*: megaloblast
Megaloblastic haematopoiesis- BM
Giant metamyelocytes and bands in neutrophil series are usually present. Detection of these cells is diagnostically important in cases, when megaloblastic features of erythropoiesis are masked by co-existing iron deficiency. Granulopoiesis use to be also hyperplastic in bone marrow, although less so than erythropoiesis. / V neutrofilní řadě jsou obvykle jsou přítomny velké metamyelocyty a tyče. Detekce těchto buněk je diagnosticky důležitá v případech, kdy jsou megaloblastické rysy erytropoézy maskovány současně přítomným nedostatkem železa. Granulopoéza je v kostní dřeni rovněž zmnožena, i když méně nežli erytropoéza. Description: Giant metamyelocytes and bands in neutrophil series are usually present. Detection of these cells is diagnostically important in cases, when megaloblastic features of erythropoiesis are masked by co-existing iron deficiency. Granulopoiesis use to be also hyperplastic in bone marrow, although less so than erythropoiesis.
Type: bone marrow
Klíčová slova*: giant band cell, giant metamyelocyte
Megaloblastic haematopoiesis- BM
There is the giant metamyelocyte at 6 o'clock at a typical change in granulocytic lineage. It is approximately twice times the size of a normal metamyelocyte with abnormal shape of nuclei. There is a hypersegmented neutrophil at right. / Na 6. hodině je gigantický metamyelocyt jako typická změna v granulocytární řadě. Je přibližně dvakrát větší nežli normální metamyelocyt s abnormálním tvarem jádra. Vpravo je hypersegmentovaný neutrofil. Description: There is the giant metamyelocyte at 6 o'clock at a typical change in granulocytic lineage. It is approximately twice times the size of a normal metamyelocyte with abnormal shape of nuclei. There is a hypersegmented neutrophil at right.
Type: bone marrow
Klíčová slova*: metamyelocyte, giant metamyelocyte
Megaloblastic erythropoiesis- BM
Hyperplastic erythropoiesis with numerous megaloblasts of various degree of maturity. / Hyperplastická erytropoéza s četnými megaloblasty různého stupně zralosti. Description: Hyperplastic erythropoiesis with numerous megaloblasts of various degree of maturity.
Type: bone marrow
Klíčová slova*: megaloblast
Megaloblastic haematopoiesis- BM
Erythropoiesis is hyperplastic and is characterized by the presence of megaloblasts. They are large erythroid cells with a chromatin pattern more immature than is appropriate for the degree of maturation of the cytoplasm. The most typical cell is at the 8 o'clock. / Erytropoéza je hyperplastická a je charakterizována přítomností megaloblastů. Jsou to velké erytroidní buňky se strukturou chromatinu méně zralou, než by odpovídalo stupni vyzrávání cytoplazmy. Nejvíce typická buňka je na 8. hodině. Description: Erythropoiesis is hyperplastic and is characterized by the presence of megaloblasts. They are large erythroid cells with a chromatin pattern more immature than is appropriate for the degree of maturation of the cytoplasm. The most typical cell is at the 8 o'clock.
Type: bone marrow
Klíčová slova*: megaloblast
MDS RAEB I- bone marrow
Early megaloblast (at right) and dysplastic late erythroblast (at left; it has non-round nucleus and basophilic stippling). Myeloblast with some azurophilic granules in Golgi zone is under the megaloblast. / Časný megaloblast (vpravo) a dysplastický pozdní erytroblast (vlevo; má zneokrouhlené jádro a basofilní tečkování). Myeloblast s několika azurofilními granuly v Golgiho zóně je pod megaloblastem. Description: Early megaloblast (at right) and dysplastic late erythroblast (at left; it has non-round nucleus and basophilic stippling). Myeloblast with some azurophilic granules in Golgi zone is under the megaloblast.
Type: bone marrow
Klíčová slova*: myeloblast, erythroblast, megaloblast
MDS RAEB II
In the upper part of the picture note a myeloblast wiht Auer rods, and nucleoli. Below this cell there is a plasmatic cell and two promyelocytes. On the right there is a group of two megaloblasts and two normoblast. / V horní části obrázku leží myeloblast s několika Auerovými tyčemi, v jádře zřetelná jadérka, pod ním plasmatická buňka a dva promyelocyty. Vpravo skupina erytroblastů se 2 normoblasty a 2 megaloblasty. Description: In the upper part of the picture note a myeloblast wiht Auer rods, and nucleoli. Below this cell there is a plasmatic cell and two promyelocytes. On the right there is a group of two megaloblasts and two normoblast.
Type: bone marrow
Klíčová slova*: myeloblast, normoblast, plasma cell, megaloblast, Auer rod
MDS RAEB II
Three blasts. In the cytoplasm of the blast in the middle, there are clearly seen Auer's rods. Below the myelocyte there is a megaloblast. Hypergranulation in cells of myeloid lineage. / Na obrázku 3 blasty, v cyoplasmě prostředního zřetelné Auer.tyče. Pod myelocytem megaloblast. Hypergranulace v buňkách myelořady. Description: Three blasts. In the cytoplasm of the blast in the middle, there are clearly seen Auer's rods. Below the myelocyte there is a megaloblast. Hypergranulation in cells of myeloid lineage.
Type: bone marrow
Klíčová slova*: myelocyte, megaloblast, Auer rod, hypergranulation
MDS RAEB II
A nest of dysplastic megakaryocytes and megakaryoblasts. / Na obrázku hnízdo dysplastických megakaryocytů a megakaryoblastů. Description: A nest of dysplastic megakaryocytes and megakaryoblasts.
Type: bone marrow
Klíčová slova*: megakaryoblast, megaloblast