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Nalezené studie* (n=1)
id | název* | obrázků* | autor* | vytvořeno* | modifikováno* | schváleno* | schválil* |
---|---|---|---|---|---|---|---|
158 | cs: Megaloblastová anémie en: Megaloblastic anemia |
19 | Monika Antošová, A. Buliková, J. Kissová | 27.5.2008, 21:43 | 20.6.2008, 13:40 | 20.6.2008, 13:40 | J. Kissová |
Nalezené obrázky* (n=15)
AML with multilineage dysplasia - BM
Description: The myeloblasts are the most frequent cells of the picture, some of them are in mitosis. In erythroid lineage are megaloblastoid features - markedly expressed in two cells at 4-5 o'clock. Hypogranulation is in neutrophils.
Type: bone marrow
Klíčová slova*: myeloblast, hypogranulation, megaloblastic haematopoiesis
Description: The myeloblasts are the most frequent cells of the picture, some of them are in mitosis. In erythroid lineage are megaloblastoid features - markedly expressed in two cells at 4-5 o'clock. Hypogranulation is in neutrophils.
Type: bone marrow
Klíčová slova*: myeloblast, hypogranulation, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Description: Numerous myeloblast and cells of erythroid lineage (almost 50%) are dominant populations of the cells of the bone marrow smear. The cells of erythroid series show dysplastic features - multilobularity, non-round nucleus shape (at 11o'clock), megaloblastoid features (at 9 o'clock) and failure of cytoplasm hemoglobinization (at 3 o'clock).
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis
Description: Numerous myeloblast and cells of erythroid lineage (almost 50%) are dominant populations of the cells of the bone marrow smear. The cells of erythroid series show dysplastic features - multilobularity, non-round nucleus shape (at 11o'clock), megaloblastoid features (at 9 o'clock) and failure of cytoplasm hemoglobinization (at 3 o'clock).
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Description: There are seven myeloblasts underneath the centre of the picture and three proerythroblasts at the upper left. Between these two groups of the cells lies one agranular band and one red mitosis. Two early polychromatophil red cells precursors (upper left) have megaloblastoid nuclear pattern and they are bilobated. Three late polychromatophil normoblasts (to the left and down from the centre) have pycnotic nuclei.
Type: bone marrow
Klíčová slova*: myeloblast, proerythroblast, polychromatophilic normoblast, megaloblastic haematopoiesis
Description: There are seven myeloblasts underneath the centre of the picture and three proerythroblasts at the upper left. Between these two groups of the cells lies one agranular band and one red mitosis. Two early polychromatophil red cells precursors (upper left) have megaloblastoid nuclear pattern and they are bilobated. Three late polychromatophil normoblasts (to the left and down from the centre) have pycnotic nuclei.
Type: bone marrow
Klíčová slova*: myeloblast, proerythroblast, polychromatophilic normoblast, megaloblastic haematopoiesis
AML with multilineage dysplasia - BM
Description: Myeloblasts represent about 30% of all nucleated bone marrow cells. There is also erythroid hyperplasia here - almost 50% in bone marrow cells differential count. Cells of erythroid lineage show dysplastic features - megaloblastic nuclei, bilnuclear cells or nuclear lobulisation, internuclear bridges, poorly hemoglobinised cytoplasm. These dysplastic features are presented in more than 50% of erythroid cells.
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis, internuclear bridges
Description: Myeloblasts represent about 30% of all nucleated bone marrow cells. There is also erythroid hyperplasia here - almost 50% in bone marrow cells differential count. Cells of erythroid lineage show dysplastic features - megaloblastic nuclei, bilnuclear cells or nuclear lobulisation, internuclear bridges, poorly hemoglobinised cytoplasm. These dysplastic features are presented in more than 50% of erythroid cells.
Type: bone marrow
Klíčová slova*: myeloblast, megaloblastic haematopoiesis, internuclear bridges
Megaloblastic haematopoiesis- PB
Description: There are macrocytes and also characteristic oval macrocytes in peripheral blood smear. There is also some degree of anisocytosis and poikilocytosis in this rather severe case, including the presence of tear-drop poikilocytes, fragments.
Type: peripheral blood
Klíčová slova*: poikilocyte, makrocyte, anisocytosis
Description: There are macrocytes and also characteristic oval macrocytes in peripheral blood smear. There is also some degree of anisocytosis and poikilocytosis in this rather severe case, including the presence of tear-drop poikilocytes, fragments.
Type: peripheral blood
Klíčová slova*: poikilocyte, makrocyte, anisocytosis
Megaloblastic haematopoiesis- PB
Description: Cabot ring can be find in severe case of megaloblastic erythropoiesis.
Type: peripheral blood
Klíčová slova*: Cabot ring
Description: Cabot ring can be find in severe case of megaloblastic erythropoiesis.
Type: peripheral blood
Klíčová slova*: Cabot ring
Megaloblastic haematopoiesis- PB
Description: The presence of hypersegmented neutrophils is highly suggestive of megaloblastic haematopoiesis in peripheral blood smear although not patognomic. It persists for a week or more after commencement of of vitamin B12 or folic acid therapy.
Type: peripheral blood
Klíčová slova*: hypersegmentation
Description: The presence of hypersegmented neutrophils is highly suggestive of megaloblastic haematopoiesis in peripheral blood smear although not patognomic. It persists for a week or more after commencement of of vitamin B12 or folic acid therapy.
Type: peripheral blood
Klíčová slova*: hypersegmentation
Megaloblastic haematopoiesis- BM
Description: Siderotic granules in Pearl's stain in sideroblast are abnormally prominent, sometimes occasional ring sideroblast can also occur (not shown).
Type: bone marrow
Klíčová slova*: sideroblast, iron stain, Perls´stain
Description: Siderotic granules in Pearl's stain in sideroblast are abnormally prominent, sometimes occasional ring sideroblast can also occur (not shown).
Type: bone marrow
Klíčová slova*: sideroblast, iron stain, Perls´stain
Megaloblastic haematopoiesis- BM
Description: Mitoses are more frequent in bone marrow (mitosis of granulocytic lineage at left, erythroid mitosis at right). Cell in metaphase shows that chromosomes are unusually long.
Type: bone marrow
Klíčová slova*: mitosis
Description: Mitoses are more frequent in bone marrow (mitosis of granulocytic lineage at left, erythroid mitosis at right). Cell in metaphase shows that chromosomes are unusually long.
Type: bone marrow
Klíčová slova*: mitosis
Megaloblastic haematopoiesis- BM
Description: Megaloblastic erythropoiesis is ineffective, early erythroid cells are over-represented in comparison with mature cells. Macrophages are increased and contain defective red cell precursors and cellular debris.
Type: bone marrow
Klíčová slova*: macrophage, haemophagocytosis
Description: Megaloblastic erythropoiesis is ineffective, early erythroid cells are over-represented in comparison with mature cells. Macrophages are increased and contain defective red cell precursors and cellular debris.
Type: bone marrow
Klíčová slova*: macrophage, haemophagocytosis
Megaloblastic haematopoiesis- BM
Description: Hypersegmented moderately mature megakaryocyte.
Type: bone marrow
Klíčová slova*: megakaryocyte
Description: Hypersegmented moderately mature megakaryocyte.
Type: bone marrow
Klíčová slova*: megakaryocyte
Megaloblastic haematopoiesis- BM
Description: Mature megakaryocyt with more finely stippled chromatin then normal megakaryocytes.
Type: bone marrow
Klíčová slova*: megakaryocyte
Description: Mature megakaryocyt with more finely stippled chromatin then normal megakaryocytes.
Type: bone marrow
Klíčová slova*: megakaryocyte
Megaloblastic haematopoiesis- BM
Description: Giant metamyelocytes and bands in neutrophil series are usually present. Detection of these cells is diagnostically important in cases, when megaloblastic features of erythropoiesis are masked by co-existing iron deficiency. Granulopoiesis use to be also hyperplastic in bone marrow, although less so than erythropoiesis.
Type: bone marrow
Klíčová slova*: giant band cell, giant metamyelocyte
Description: Giant metamyelocytes and bands in neutrophil series are usually present. Detection of these cells is diagnostically important in cases, when megaloblastic features of erythropoiesis are masked by co-existing iron deficiency. Granulopoiesis use to be also hyperplastic in bone marrow, although less so than erythropoiesis.
Type: bone marrow
Klíčová slova*: giant band cell, giant metamyelocyte
Megaloblastic haematopoiesis- BM
Description: There is the giant metamyelocyte at 6 o'clock at a typical change in granulocytic lineage. It is approximately twice times the size of a normal metamyelocyte with abnormal shape of nuclei. There is a hypersegmented neutrophil at right.
Type: bone marrow
Klíčová slova*: metamyelocyte, giant metamyelocyte
Description: There is the giant metamyelocyte at 6 o'clock at a typical change in granulocytic lineage. It is approximately twice times the size of a normal metamyelocyte with abnormal shape of nuclei. There is a hypersegmented neutrophil at right.
Type: bone marrow
Klíčová slova*: metamyelocyte, giant metamyelocyte
Megaloblastic haematopoiesis- BM
Description: Erythropoiesis is hyperplastic and is characterized by the presence of megaloblasts. They are large erythroid cells with a chromatin pattern more immature than is appropriate for the degree of maturation of the cytoplasm. The most typical cell is at the 8 o'clock.
Type: bone marrow
Klíčová slova*: megaloblast
Description: Erythropoiesis is hyperplastic and is characterized by the presence of megaloblasts. They are large erythroid cells with a chromatin pattern more immature than is appropriate for the degree of maturation of the cytoplasm. The most typical cell is at the 8 o'clock.
Type: bone marrow
Klíčová slova*: megaloblast