Ropheocytose

Autor*: Ondřej Zapletal, Helena Fišárková, Ondřej Zapletal, J. Kissová

Description:
Ropheocytosis is a transport of ferritin and hemosiderin form macrophage to erythroblasts. Erythroblastic "island": macrophage (siderophage) surrounded with cluster of erythroblasts. The macrophage phagocytoses defective erythroblasts and extruded erythroblast nuclei. 4-years old girl, treated for ALL, BM aspirate within remision.

Zařazení*:
Normal blood and blood marrow cells

Přílohy*:

Erythroblastic island
Macrophage (in center) surrounded by cluster of mature erythroblasts. The macrophage phagocytoses defective erythroblasts and extruded erythroblast nuclei. Macrophage also serves as a "iron store" for erythroblasts. / Makrofág (siderofág) uprostřed slouží jako zásobárna Fe. Je obklopený koncentrickým prstencem vyzrávajících polychromatofilních normoblastů. Makrofág fagocytuje defektní erytroblasty a jádra, která jsou v průběhu zrání z erytroblastů vyloučena. 
Description: Macrophage (in center) surrounded by cluster of mature erythroblasts. The macrophage phagocytoses defective erythroblasts and extruded erythroblast nuclei. Macrophage also serves as a "iron store" for erythroblasts.
Type: bone marrow
Klíčová slova*: macrophage, normoblast, erythroblast, orthochromatophilic normoblast
Erythroblastic island
Concentric circles of erythroblasts closely surround a macrophage, those closer to the macrophage are less mature. Macrophage sends slender processes which envelop each erythroblast. / Koncentrické kruhy erytroblastů kolem makrofágu, vnější jsou zralejší. Štíhlé výběžky cytoplasmy makrofágu obkloupují erytroblasty. Description: Concentric circles of erythroblasts closely surround a macrophage, those closer to the macrophage are less mature. Macrophage sends slender processes which envelop each erythroblast.
Type: bone marrow
Klíčová slova*: macrophage, normoblast, erythroblast
Erythroblastic island - Perls´ stain
Cumulation of iron (hemosiderin) in macrophage. / Při barvení na nehemové železo je patrná jeho kumulace v makrofágu. Description: Cumulation of iron (hemosiderin) in macrophage.
Type: bone marrow
Klíčová slova*: macrophage, normoblast
Erythroblastic island - Perls´ stain
see previous / viz předchozí Description: see previous
Type: bone marrow
Klíčová slova*: macrophage, normoblast