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AML with multilineage dysplasia - BM
Three myeloblast and six erythroid cells (and one naked nucleus) are in the picture. Two immature erythroid cells with abundant basophilic cytoplasm are megalobasts. At the lower left is one more cell probably of granulocytic lineage; it has a few cytoplasmic a one nuclear inclusions of not clear origin - some of them can be digestive ones after haemophagocytosis (one at 6 o'clock in the cell). / Na obrázku jsou tři myeloblasty a šest buněk erytropoezy (a jedno holé jádro). Dvě nezralé erytroidní buňky s bohatou bazofilní cytoplazmou jsou megaloblasty. Nalevo dole je jedna buňka pravděpodobně granulocytární řady; má pár cytoplazmatických a jednu jadernou inkluzi nejasného původu - některé z nich mohou být ztrávené po hemofagocytóze (jedna na 5. hodině v buňce). Description: Three myeloblast and six erythroid cells (and one naked nucleus) are in the picture. Two immature erythroid cells with abundant basophilic cytoplasm are megalobasts. At the lower left is one more cell probably of granulocytic lineage; it has a few cytoplasmic a one nuclear inclusions of not clear origin - some of them can be digestive ones after haemophagocytosis (one at 6 o'clock in the cell).
Type: bone marrow
Klíčová slova*: myeloblast, megaloblast, haemophagocytosis
Small - cell bronchial carcinoma - BM
Tumour cells' infiltration - cluster of various size immature cells with narrow cytoplasm's rim, fine chromatin and nucleoli; there is late erythroblast at the upper right and there are some naked nucleoli at the smear. / Infiltrace nádorovými buňkami - trs různě velkých buněk s úzkým lemem cytoplazmy, v jádře jemný chromatin a jadérka, v nátěru je vpravo nahoře pozdní erytroblast a několik holých jáder. Description: Tumour cells' infiltration - cluster of various size immature cells with narrow cytoplasm's rim, fine chromatin and nucleoli; there is late erythroblast at the upper right and there are some naked nucleoli at the smear.
Type: bone marrow
Klíčová slova*: orthochromatophilic normoblast, naked nucleus, tumour cell
Small- cell bronchial carcinoma - BM
Tumour cells' infiltration of the bone marrow - cluster of smaller to middle size cells with high nucleus - cytoplasm ratio, there is fine chromatin in the nucleus with one to more nucleoli. There is one hypergranular neutrophile myelocyte at left side, segmented neuthrophil with pseudo-pelgeroid appearance at the top and late erythroblast at the upper left, there are same naked nucleoli at the smear. / Infiltrace nádorovými buňkami - trs menších a středně velkých buněk s vysokým poměrem jádra a cytoplazmy, v jádře jemný chromatin s jedním až několika jadérky. Vlevo je jeden hypergranulovaný neutrofilní myelocyt, nahoře neutrofilní segment pseudo-pelgeroidního vzhledu a vpravo nahoře pozdní erytroblast, v nátěru je také několik holých jader. Description: Tumour cells' infiltration of the bone marrow - cluster of smaller to middle size cells with high nucleus - cytoplasm ratio, there is fine chromatin in the nucleus with one to more nucleoli. There is one hypergranular neutrophile myelocyte at left side, segmented neuthrophil with pseudo-pelgeroid appearance at the top and late erythroblast at the upper left, there are same naked nucleoli at the smear.
Type: bone marrow
Klíčová slova*: myelocyte, orthochromatophilic normoblast, hypergranulation, naked nucleus, tumour cell
Small- cell bronchial carcinoma - BM
The first example of the bone marrow infiltration in this case - the cluster of the middle size cells with narrow rim of basophilic cytoplasm; there is fine chromatin and some nucleoli in the nucleus. There is eosinophil metamyelocyte at the upper left, neutrophil metamyelocyte at the upper right and there are two late erythroblasts at the upper part of the picture. Naked nucleoli are the typical content of the smear. / První příklad infiltrace nádorovými buňkami u tohoto případu - trs středně velkých buněk s úzkým lemem bazofilní cytoplamy; v jádře je jemný chromatin a jadérka. Vlevo nahoře eosinofilní metamyelocyt, vpravo nahoře neutrofilní metamyelocyt, v horní části obrázku dva pozdní erytroblasty. Holá jádra jsou typickou součástí nátěru. Description: The first example of the bone marrow infiltration in this case - the cluster of the middle size cells with narrow rim of basophilic cytoplasm; there is fine chromatin and some nucleoli in the nucleus. There is eosinophil metamyelocyte at the upper left, neutrophil metamyelocyte at the upper right and there are two late erythroblasts at the upper part of the picture. Naked nucleoli are the typical content of the smear.
Type: bone marrow
Klíčová slova*: metamyelocyte, orthochromatophilic normoblast, naked nucleus, tumour cell