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Splenic marginal zone B-cell lymphoma
The most of lymphocytes in the picture belong to lymphoma cells. But that one at 5 o'clock is large granular lymphocyte (LGL) - it means NK cell or mature T lymphocyte. Also lymphocyte at 4 o'clock does not seems to be lymphoma cell. It can be reactive lymphocyte according to pale cytoplasm with more basophilic rim. / Většina lymfocytů na obrázku patří k lymfomovým buňkám. Ale ta na 5. hodině je velký granulovaný lymfocyt (LGL) - to znamená NK buňka či zralý T lymfocyt. Také lymfocyt na 4. hodině se nezdá být buňkou lymfomovou. Může jít o reaktivní lymfocyt podle světlé cytoplazmy s více bazofilním okrajem. Description: The most of lymphocytes in the picture belong to lymphoma cells. But that one at 5 o'clock is large granular lymphocyte (LGL) - it means NK cell or mature T lymphocyte. Also lymphocyte at 4 o'clock does not seems to be lymphoma cell. It can be reactive lymphocyte according to pale cytoplasm with more basophilic rim.
Type: bone marrow
Klíčová slova*: lymphocyte reactive, large granular lymphocyte, lymphocyte atypical
Splenic marginal zone B- cell lymphoma
Numerous villous lymphocytes in bone marrow smear. Some show nucleoli in their nuclei. There is segmented neutrophil underneath the centre of the picture and one large granular lymphocyte at 5 o' clock. / Početné vilózní lymfocyty v nátěru kostní dřeně. Některé mají jadérka v jádrech. Jeden neutrofilní segment je pod středem obrázku a velký granulovaný lymfocyt na 5. hodině. Description: Numerous villous lymphocytes in bone marrow smear. Some show nucleoli in their nuclei. There is segmented neutrophil underneath the centre of the picture and one large granular lymphocyte at 5 o' clock.
Type: bone marrow
Klíčová slova*: large granular lymphocyte, lymphocyte atypical