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Small- cell bronchial carcinoma - BM
Tumour cells' infiltration of the bone marrow - cluster of smaller to middle size cells with high nucleus - cytoplasm ratio, there is fine chromatin in the nucleus with one to more nucleoli. There is one hypergranular neutrophile myelocyte at left side, segmented neuthrophil with pseudo-pelgeroid appearance at the top and late erythroblast at the upper left, there are same naked nucleoli at the smear. / Infiltrace nádorovými buňkami - trs menších a středně velkých buněk s vysokým poměrem jádra a cytoplazmy, v jádře jemný chromatin s jedním až několika jadérky. Vlevo je jeden hypergranulovaný neutrofilní myelocyt, nahoře neutrofilní segment pseudo-pelgeroidního vzhledu a vpravo nahoře pozdní erytroblast, v nátěru je také několik holých jader. Description: Tumour cells' infiltration of the bone marrow - cluster of smaller to middle size cells with high nucleus - cytoplasm ratio, there is fine chromatin in the nucleus with one to more nucleoli. There is one hypergranular neutrophile myelocyte at left side, segmented neuthrophil with pseudo-pelgeroid appearance at the top and late erythroblast at the upper left, there are same naked nucleoli at the smear.
Type: bone marrow
Klíčová slova*: myelocyte, orthochromatophilic normoblast, hypergranulation, naked nucleus, tumour cell
MDS RAEB II
In the middle of this picture you can see a blast with clear Auer rods (visible clear nucleoli). On the left there is a large metamyelocyte. In cells of myeloid lineage a dense hypergranulation is visible. / Uprostřed obrázku blast s Auerovými tyčemi (zřetelná jadérka). Na levo velký metamyelocyt . Hrubá hypergranulace v buňkách myelořady. Description: In the middle of this picture you can see a blast with clear Auer rods (visible clear nucleoli). On the left there is a large metamyelocyte. In cells of myeloid lineage a dense hypergranulation is visible.
Type: bone marrow
Klíčová slova*: Auer rod, hypergranulation, giant metamyelocyte
MDS RAEB II
Three blasts. In the cytoplasm of the blast in the middle, there are clearly seen Auer's rods. Below the myelocyte there is a megaloblast. Hypergranulation in cells of myeloid lineage. / Na obrázku 3 blasty, v cyoplasmě prostředního zřetelné Auer.tyče. Pod myelocytem megaloblast. Hypergranulace v buňkách myelořady. Description: Three blasts. In the cytoplasm of the blast in the middle, there are clearly seen Auer's rods. Below the myelocyte there is a megaloblast. Hypergranulation in cells of myeloid lineage.
Type: bone marrow
Klíčová slova*: myelocyte, megaloblast, Auer rod, hypergranulation
APL- bone marrow 3
At centre of the picture are two "faggot cells" on the right, two abnormal hypergranular promyelocytes on the left- one with cleaved or bilobated nucleus. Below are two hypergranular myelocytes with large reddish inclusions- upper myelocyt with cleaved nucleus, both of them are impaired. / Uprostřed snímku jsou dvě "faggot cells" vpravo, dva abnormální hypergranulované promyelocyty vlevo- jeden s rozštěpeným nebo dvoulaločnatým jádrem. Pod nimi dva hypergranulované myelocyty s objemnými inkluzemi- horní buňka s rozštěpeným jádrem, obě jsou poškozené. Description: At centre of the picture are two "faggot cells" on the right, two abnormal hypergranular promyelocytes on the left- one with cleaved or bilobated nucleus. Below are two hypergranular myelocytes with large reddish inclusions- upper myelocyt with cleaved nucleus, both of them are impaired.
Type: bone marrow
Klíčová slova*: myelocyte, faggot cell, hypergranulation
APL- bone marrow 2
Smear shows "faggot cells" with numerous Auer rods, myeloblasts and above to the left hypergranulated myelocyte. / Nátěr ukazuje "faggot cells" s početnými Auerovými tyčemi, vlevo nahoře hypergranulovaný myelocyt. Description: Smear shows "faggot cells" with numerous Auer rods, myeloblasts and above to the left hypergranulated myelocyte.
Type: bone marrow
Klíčová slova*: myelocyte, Auer rod, faggot cell, hypergranulation
APL- peripheral blood 6
Pseudo Chediak-Higashi granule in hypergranulated promyelocyte. Two mature lymphocytes with short polar villi, but along the spread (artificial). / Pseudo Chediak- Higashiho granula u hypergranulovaného promyelocytu. Dva zralé lymfocyty s krátkými "vlásky" na pólech buňky, ale ve směru nátěru (arteficiálně). Description: Pseudo Chediak-Higashi granule in hypergranulated promyelocyte. Two mature lymphocytes with short polar villi, but along the spread (artificial).
Type: peripheral blood
Klíčová slova*: promyelocyte, lymphocyte, hypergranulation
APL- peripheral blood 4
Hypergranular promyelocyte with large reddish inclusion (pseudo Chediak-Higashi granule). / Hypergranulovaný promyelocyt s objemnou inkluzí (pseudo Chediak- Higashiho granula). Description: Hypergranular promyelocyte with large reddish inclusion (pseudo Chediak-Higashi granule).
Type: peripheral blood
Klíčová slova*: promyelocyte, hypergranulation