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microgranular variant APL- BM

Autor*: A. Buliková, J. Kissová

microgranular variant APL- BM

Description:
In all cases of acute leukaemia with bilobar nuclei it is really necessary carefully search for cells with bundles Auer rods in cytoplasm ("faggot cells"). This finding brings high suspicion to diagnose of microgranular variant of APL, which should be confirmed by cytogenetic and/or molecular genetic examination - presence of t(15;17) and/or PML/RARalfa fusion gene.

Type:
bone marrow

Klíčová slova*:
promyelocyte, Auer rod, faggot cell